Preparation and characterization of tetrandrine-phospholipid complex loaded lipid nanocapsules as potential oral carriers
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چکیده
منابع مشابه
Preparation and characterization of tetrandrine-phospholipid complex loaded lipid nanocapsules as potential oral carriers
BACKGROUND Tetrandrine is an active constituent that is extracted from the root tuber of the Chinese herb Stephania tetrandra S. Moore. It has shown various pharmacological effects, such as antitumor activity, multidrug resistance reversal, and hepatic fibrosis resistance. In clinical applications, it has been used to treat hypertension, pneumosilicosis, and lung cancer. However, the poor water...
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Zerumbone, a natural dietary lipophilic compound with low water solubility (1.296 mg/L at 25°C) was used in this investigation. The zerumbone was loaded into nanostructured lipid carriers using a hot, high-pressure homogenization technique. The physicochemical properties of the zerumbone-loaded nanostructured lipid carriers (ZER-NLC) were determined. The ZER-NLC particles had an average size of...
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ژورنال
عنوان ژورنال: International Journal of Nanomedicine
سال: 2013
ISSN: 1178-2013
DOI: 10.2147/ijn.s50557